Maryland-based Altimmune is a biopharmaceutical company that focuses on developing vaccines delivered by nasal spray. Then they manufacture RNA molecules encoding the rewritten genes. They project manufacturing up to 300 million doses in 2021 and up to a billion doses the following year. In January, the company announced they were also starting preclinical research on a vaccine tailored specifically to newly emerged coronavirus variants that could potentially evade conventional vaccines. On April 29, they registered a Phase 1 trial in Turkey. Storage: Refrigerated Phase 3 differs from the two previous phases in taking a staggered approach to reopening. Speaking to Sky News the day after Boris Johnson’s speech, Dominic Raab explained: ‘From the earliest, June 1, we’ll look at non-essential retail and how they can go back, only if the conditions are met, subject to wider monitoring, so that we only proceed in a sure-footed way. But generally, 3-phase power is mostly used over 1-phase power because 3-phase machinery is more sufficient than a 1-phase. Type: Muscle injection A Phase 1/2 trial then showed that the vaccine didn’t cause any serious side effects and enabled people to make antibodies against the coronavirus. On Dec. 14, the president of the university said that the Phase 1 trial was complete. European medical regulators became concerned about a small number of cases of blood clots in younger people who received Vaxzevria. The Russian developers pushed back against Anvisa’s claims and said they would sue for defamation.In January 2021, Gamaleya researchers started a trial in which they gave people only the first dose of Ad26 adenoviruses, the same adenovirus in Johnson & Johnson’s single-dose vaccine. They are betting it can offer long-lasting immunity. APPROVED IN CHINA In August, Arcturus launched a Phase 1/2 trial at Singapore General Hospital. On May 7, Pfizer and BioNTech announced they would seek full F.D.A. PHASE 3 Updated April 5, ABANDONED Developing an alternative formulation that can be refrigerated. Marvel Cinematic Universe: Phase Three, eleven American superhero films from 2016–2019; Phase 3: Thrones and Dominions, a 1995 album by Earth; Phase III, a 1972 album by The Osmonds; Phase Three, a 2003 album by The Riverdales; Other. They began a Phase 1/2 trial of their vaccine, known as AKS-452, on April 12. At least 15 million doses of Johnson & Johnson’s vaccine were contaminated at the factory.As a result, the company only delivered 4 million doses to the United States after authorization, shipping them from its factory in the Netherlands. On April 13 the U.S. government recommended a pause in using the vaccine while it investigated reports of rare blood clots. In Brazil, the efficacy against Covid-19 with or without symptoms was 50 percent. The details of the Phase 3 trial has yet to be published in a scientific journal.Last June, Beijing Institute researchers reported that the vaccine produced promising results in monkeys. They registered a Phase 1 trial in China last November. They published the results of their experiments in November.On Feb. 22, Mahidol University in Thailand registered a Phase 1 trial of the vaccine, called NDV-HXP-S. Researchers at Baltimore-based Elixirgen Therapeutics have created an RNA vaccine, named EXG-5003, that targets a small part of the coronavirus spike protein. On Feb. 3, Vaxart announced that the trial revealed no serious safety concerns. Approved for use in: China. As an example, let’s use a 3 phase 208 volt line. For more details, see How the Pfizer-BioNTech Vaccine Works and How Pfizer Makes Its Covid-19 Vaccine. Emergency use in U.S., E.U., other countries. Emergency use in: Albania NEW, Algeria, Angola, Antigua and Barbuda, Argentina, Armenia, Azerbaijan, Bahrain, Bangladesh NEW, Belarus, Bolivia, Bosnian Serb Republic, Cameroon, Congo Republic, Djibouti, Egypt, Honduras, Gabon, Ghana, Guatemala, Guinea, Guyana, Hungary, India, Iran, Iraq, Jordan, Kazakhstan, Kenya, Kyrgyzstan, Laos, Lebanon, Mali, Mauritius, Mexico, Moldova, Mongolia, Montenegro, Morocco, Myanmar, Namibia, Nepal, Nicaragua, North Macedonia, Pakistan, Palestinian Authority, Panama, Paraguay, Philippines, San Marino, Slovakia, Sri Lanka, St. Vincent and the Grenadines, Serbia, Seychelles, Syria, Tunisia, Turkey NEW, Turkmenistan, United Arab Emirates, Uzbekistan, Venezuela, Vietnam, Zimbabwe. Updated March 20, PRECLINICAL The trial will determine whether the vaccine provides as much protection for them as for women who aren’t pregnant, and also gather information on its safety. Sorry, this video isn't available any more. These trials can determine if the vaccine protects against the coronavirus, measuring what’s known as the efficacy rate. Updated March 20, PHASE 1 PHASE 2 COMBINED PHASES Nevertheless, the vaccine’s low cost and ease of storage made it attractive to countries looking for a way out of the pandemic. Updated May 7, PHASE 1 Updated April 26, PHASE 3 In October 2020, Entos launched a Phase 1 trial in Canada for their vaccine, called Covigenix VAX-001. Updated Feb. 10, PHASE 1 Restaurants, bars, gyms and other businesses can continue at the current Phase 3 50 percent capacity requirement for now. The Italian biotechnology company ReiThera has developed a Covid-19 vaccine, called GRAd-COV2, that is based on an adenovirus that infects gorillas. The company expects to move into Phase 2 trials by May. Since then, the Trump and Biden administrations reached agreements for a total of 300 million doses by the summer. Emergency use in: Algeria, Argentina, Australia, Bahamas, Bahrain, Bangladesh, Barbados, Bhutan, Botswana, Brazil, Brunei, Canada, Chile, Colombia, Costa Rica, Dominican Republic, Ecuador, Egypt, El Salvador, Ethiopia NEW, European Union, Fiji, Georgia NEW, Ghana, Greenland, Guatemala, Honduras, Hungary, Iceland, India, Indonesia, Iran, Iraq, Jamaica NEW, Kenya, Kuwait, Liechtenstein, Malaysia, Maldives, Mexico, Moldova, Mongolia, Morocco, Namibia, Nepal, Nigeria, North Macedonia, Norway, Pakistan, Papua New Guinea, Peru, Philippines, Saudi Arabia, Seychelles, Sri Lanka, South Africa, South Korea, Sudan, Taiwan, Thailand, Ukraine, United Kingdom, Vietnam, Zambia. While it provided promising levels of antibodies in people under 50, older people did not respond as strongly as they had hoped. On May 4, 2021 HDT announced the trial was underway in India. Vaccine name: CoronaVac (formerly PiCoVacc) Because the coronaviruses that cause SARS and Covid-19 are very similar, the researchers revived the project in partnership with the Texas Children’s Hospital. Known as COVIran Barekat, it entered a Phase 1 trial at the end of December. Scientific and Technological Research Council of Turkey, the first to put a Covid-19 vaccine into human trials, published the results of their Phase 3 trial, They began using Johnson & Johnson’s instead, no longer use Johnson & Johnson’s vaccine, the effects of two doses of their vaccine, faced delays in recruiting enough participants for their Phase 1 study, Covid-19 vaccine based on a virus called Newcastle Disease Virus, Institute of Vaccines and Medical Biologicals, 96 percent against the original coronavirus, Investments from the Coalition for Epidemic Preparedness, with the European Union for 300 million doses, ones that have yet to spill over from animal hosts, inactivated coronaviruses to develop immunity, the first coronavirus vaccine created in India, to develop Covaxin for the United States market, Frequently Asked Questions About the Covid Data, The W.H.O. The vaccine is now in a Phase 2/3 trial. The furthest along is an mRNA-based vaccine known as ChulaCov19. On Nov. 2, the Canadian company Symvivo announced they had administered a DNA vaccine to their first volunteer in a Phase 1 trial. Updated Nov. 7. What is Phase 3 of lockdown? The following industries are set to reopen during this time: Hotels and Resorts (June 2020) Parks – broader reopening, including some overnight camping (June 2020) A team of Turkish researchers at Middle East Technical University and Bilkent University have developed a vaccine that is made up of virus-like particles. Vietnam news agencies announced that Nanocovax entered Phase 2 trials in February. Known as Mambisa, the vaccine contains a piece of the coronavirus spike protein called the receptor-binding domain, along with a protein from the hepatitis B virus that stimulates the immune system. Three decades ago, the German Center for Infection Research developed a smallpox vaccine from a harmless virus called Modified Vaccinia Ankara, or MVA for short. In an April 29 interview, the managing director of Zydus Cadila said that the trial could deliver efficacy results in May, after which the company will immediately seek emergency authorization from the Indian government. At least 77 preclinical vaccines are under active investigation in animals. LIMITED USE IN U.A.E. The European Union began a rolling review in February, intended to speed up approval if the Phase 3 trial delivers positive results. Once the shell slips into a cell, the RNA molecule can make copies of itself, and the cell then makes proteins from those copies.In a Phase 1 trial launched in March, the National Institute of Allergy and Infectious Diseases is testing how well these two vaccines work together, with the chimpanzee adenovirus serving as the first dose and the self-amplifying RNA as the second. VIDO registered a Phase 1/2 trial on Jan. 8. Some vaccines contain whole proteins, and some contain fragments of them. Finally, on Nov. 9, Pfizer and BioNTech released their preliminary analysis of the first 94 cases.Over the next month, Pfizer and BioNTech released more data on more cases. Along with their Beijing Institute vaccine, Sinopharm also tested an inactivated virus vaccine developed by the Wuhan Institute of Biological Products. Efficacy: Unknown Approved for use in: Switzerland. The study has not yet been published in a medical journal.For more details, see How the Sinopharm Vaccine Works. They launched a Phase 2 trial on ZyCoV-D on Aug. 6 and announced at the end of December that it was complete. On Dec. 29, Biological E and the Coalition for Epidemic Preparedness Innovations announced a partnership to advance the development and manufacturing of the vaccine, known as BECOV2, with CEPI initially contributing $5 million to the effort.On April 24, Biological E announced it was starting a Phase 3 trial. Two days later, the United States followed suit. The researchers held the proteins in place with a molecular clamp, which was based on a segment of an HIV protein.HIV tests use antibodies to probe for the presence of the virus’s proteins in people’s blood. After positive results from a Phase 1 trial, Finlay received approval to begin a Phase 2 trial among Covid-19 survivors on April 9. Entos instead chose the gene for nucleocapsid, a protein that sits inside the virus’s membrane. The researchers decorated these shells with part of the coronavirus spike protein. Last spring, researchers at the University of Washington developed a nanoparticle studded with pieces of the coronavirus spike protein. By Carl Zimmer, Jonathan Corum and Sui-Lee WeeUpdated May 10, 2021. Vaccine name: CVnCoV Researchers will then observe whether VLA2001 produces similar levels of antibodies to Vaxzevria.The company hopes to submit VLA2001 for authorization in fall 2021. In November, they announced that the vaccine was well tolerated and produced antibodies, and released a report on the trial in April 2021. On Nov. 25, Covaxx announced agreements with countries including Brazil, Ecuador, and Peru to deliver more than 140 million doses for $2.8 billion. Then they added a gene for the coronavirus spike protein, so that the weakened RSV viruses could present it to the immune system. Phase 3 allows 400 people maximum for indoor and outdoor activities as long as physical distancing and masking are enforced. The Chumakov Center at the Russian Academy of Sciences developed an inactivated coronavirus vaccine called CoviVac. On Dec. 16, Valneva launched a Phase 1/2 trial in the United Kingdom, and in April the company announced that the trial had delivered positive results. Dose: 2 doses, 4 weeks apart Vaccine name: Vaxzevria (also known as AZD1222, or Covishield in India) Limited use in: United Arab Emirates. Under Phase 3, restaurants, gyms, movie theaters and other indoor places will be able to increase capacity to 50%, up from 25% as it was in Phase 2, Gov. Did we miss something? The researchers introduced mutations into the RSV virus’s genes so that it replicated too slowly to cause disease. Oral vaccines have been approved for diseases including polio, cholera, and typhoid fever. Vaccines that contain coronavirus proteins but no genetic material. It is the second vaccine SK Bioscience has put into trials, after launching a study on another protein-based vaccine called NBP2001. On April 22, Valneva launched a Phase 3 trial on 4,000 volunteers in the United Kingdom. Some vaccines are now in Phase 1/2 trials, for example, which this tracker would count as both Phase 1 and Phase 2. The Phase 1/2 trial showed that the vaccine produced antibodies in volunteers, some of whom experienced fevers and other side effects. The vaccine contains the RBD section of the virus’s spike protein. The name refers to women who fought in Cuba’s nineteenth-century wars of independence. Early use in: Russia. On Feb. 7, South Africa halted plans for a rollout of 1 million doses of the AstraZeneca vaccine. Sinovac published the details of the trial in November in a medical journal, showing a comparatively modest production of antibodies. Less than two months later, on Oct. 14, Vladimir Putin announced that Russia has granted regulatory approval to the vaccine, making it the second one to receive that designation after the Gamaleya Institute’s Sputnik V vaccine.A Phase 3 trial began in November, and as of Dec. 15, the Interfax News Agency reported that 1,438 volunteers had received the vaccine.In January, Russia launched a mass vaccination campaign that included EpiVacCorona.. Updated May 5, PHASE 1 PHASE 2 COMBINED PHASES They are running the trial in collaboration with the Government Pharmaceutical Organization, a Thai state-run drug manufacturer. In June, The New York Times reported, a hedge fund that partly controlled the company sold off most of its shares, netting over $200 million in profits. Storage: Over a year at room temperature Updated April 1, PHASE 2 The company launched trials for a Covid-19 vaccine in May, and the Coalition for Epidemic Preparedness Innovations invested $384 million to support research on the vaccine. Updated May 7, PHASE 3 This was recently confirmed by DPM Heng Swee … Researchers at the Lanzhou Institute of Biological Products, Beijing Zhong Sheng Heng Yi Pharmaceutical Technology and Zhengzhou University are testing a vaccine that is grown in Chinese hamster ovary cells. On August 28, 2020, their Research Institute for Biological Safety Problems registered a Phase 1 trial on the vaccine. Updated May 5, PHASE 1 PHASE 3 EFFICACY TRIALS: Scientists give the vaccine to thousands of people and wait to see how many become infected, compared with volunteers who received a placebo. After an investigation, the trial may resume or be abandoned. Updated March 25. PHASE 2 EXPANDED TRIALS: Scientists give the vaccine to hundreds of people split into groups, such as children and the elderly, to see if the vaccine acts differently in them. The Massachusetts-based company VBI Vaccines developed a coronavirus vaccine that is based on hollow, virus-like protein shells. The vaccine is based on the same design Sanofi used to create Flublok, an approved vaccine for influenza. Type: Muscle injection In April, the South Korean biotech company Cellid began to develop a vaccine for Covid-19. The researchers estimated that the vaccine had an efficacy rate of 94.1 percent. In Feb. 2021, the companies announced a study to develop a B.1.351-specific booster. Emergency use in: China, Uzbekistan. The DNA is inserted into harmless bacteria, which volunteers swallow in a frozen liquid (the company is working on putting the bacteria into a pill). Known as EuCorVac-19, the vaccine combines the spike protein with an adjuvant that stimulates the immune system. They gave the vaccine the generic name tozinameran and the brand name Comirnaty In Phase 1 trials, the researchers found that Comirnaty caused volunteers to produce antibodies against SARS-CoV-2, as well as immune cells called T cells that respond to the virus. Updated Dec. 8, PHASE 2 They are exploring the possibility that such a vaccine could someday protect against a wide swath of coronaviruses, including ones that have yet to spill over from animal hosts. On Aug. 18, the head of epidemiology at Cuba’s public health ministry announced the country’s first trial of a vaccine of Covid-19. Mice don’t suffer symptoms of Covid-19, however, so the researchers then switched to hamsters, which do. Phase 3 will remain until vaccines are available When we finally enter Phase 3, Singapore will remain in that stage until a vaccine becomes available and proves to be effective. The company also found that the vaccine had an efficacy of 70 percent against Covid-19 without symptoms, suggesting that Covaxin can block the spread of the virus. However, if we put in more enablers, more activities can gradually resume under Phase Three. Clover’s formula looks to be especially durable; the vaccine can sit out at room temperature for a month and remain viable.Clover launched a Phase 1 trial last June, and in December the company announced that the vaccine triggered a high level of antibodies. Less than two months later, on Dec. 9, the U.A.E. Meissa Vaccines has developed a vaccine that can be delivered as a spray or drops into the nose. Based on 20 cases of Covid-19 among the trial participants, Russian scientists estimated that the vaccine demonstrated 92 percent efficacy. Updated Jan. 12, PHASE 1 Updated March 20, PHASE 3 The development cycle of a vaccine, from lab to clinic. The true toll of the pandemic in the U.S. How many have been vaccinated, by country, The true toll of coronavirus around the world. DeSantis announces Phase 3 of reopening, lifts restrictions on restaurant capacity Below is a detailed list of what Phase 3 means, according to the state : Individuals Type: Skin injection EMERGENCY USE IN U.S., ELSEWHERE On Aug. 26, the Vector Institute, a Russian biological research center, registered a Phase 1/2 trial for a coronavirus vaccine they call EpiVacCorona. Updated May 1, PHASE 2 Scientists at Jiangsu Rec-Biotechnology have developed a vaccine, called ReCOV, that is made of viral proteins that are grown in Chinese hamster ovary cells. Updated May 10, PHASE 3 Cuban researchers at Finlay Vaccine Institute have also developed a single-dose vaccine called Soberana Plus. After testing the vaccine on monkeys, Cellid entered into a partnership with the South Korean chemical manufacturer LG Chem to manufacture the vaccine. Approved for use in: Turkmenistan. The DNA enters cells, which use the genetic instructions to make spike proteins. gave full approval to BBIBP-CorV, announcing it had an efficacy rate of 86 percent. In December, the Korea Biomedical Review reported that Genexine got disappointing results from their initial formulation and decided to restart their trials with a modified vaccine. On Nov. 9, the company announced that an interim analysis of the trial showed that the vaccine produced an immune response that’s in the range of responses seen in people who recovered from Covid-19. Updated May 1, PHASE 2 PHASE 3 COMBINED PHASES It also makes it possible to produce a rotating magnetic field in an electric motor and generate other phase arrangements using transformers (for instance, a two phase system using a Scott-T transformer). The creators of the vaccine published the results of their Phase 3 trial on Feb. 2 in the Lancet. On April 26, the European Commission announced it had filed a lawsuit against the company for breach of contract.Yet India still struggled to vaccinate its own citizens while cases and deaths skyrocketed. Updated April 28, PHASE 3 Their candidate is composed of an adjuvant, along with a section of the spike protein called the receptor-binding domain. The name is from a poem by the nineteenth-century poet José Marti. On March 22, Japan’s KM Biologics announced that it had begun a Phase 1/2 trial of its inactivated vaccine candidate, called KD-414. If the European Medicines Agency approved it, many European countries might take up the vaccine.On April 26, the board of Brazil’s vaccine regulator rejected Sputnik V, saying that it contained adenoviruses that had not been properly disabled. Some of the proteins, from hepatitis B viruses, assemble themselves into hollow shells. By the end of the year, Russia planned on producing 20 million doses. Get support for your COVID-19 expenses & lost revenues. Efficacy: 91.3% Stopped use in: Denmark. We are currently in the second phase of lockdown, as per the measures laid out by Boris Johnson in his address to the nation on Sunday 10 May. Each of the 3 lines will be carrying 120 volts. The vaccine used a weakened measles virus that carries a gene for the coronavirus spike protein. Vaccine name: Ad26.COV2.S Approved for use in: Bahrain, Brazil, New Zealand, Saudi Arabia, Switzerland. As Singapore has made good progress to support a further resumption of activities, the Multi-Ministry Taskforce (MTF) will start Phase 3 of re-opening from 28 Dec 2020. Other RNA vaccines made by Pfizer and Moderna have to be kept frozen at chillier temperatures.Starting in January 2021, CureVac forged a series of partnerships with pharmaceutical giants Bayer, Celonic, GSK, and Novartis, to support the production of their vaccine and develop new ones against coronavirus variants. Efficacy: Unknown Dose: 2 doses, 2 weeks apart Dose: To be determined On March 29, a coalition of African countries announced that it has secured up to 400 million doses of the Johnson & Johnson vaccine through 2022. They engineered the viruses to carry the gene for the coronavirus spike protein. On Dec. 18., the F.D.A. It’s not clear how the trial will fare now that Israel is aggressively vaccinating its citizens with authorized vaccines by Pfizer. They produced the proteins with engineered viruses that grow inside insect cells. released a similar analysis on Feb. 24. Updated May 6, PHASE 1 PHASE 2 COMBINED PHASES When is the next full moon? Updated Feb. 8, PHASE 1 PHASE 2 COMBINED PHASES On Nov. 25, the company reached an agreement with the European Commission to supply up to 160 million doses. The California-based company Arcturus Therapeutics and Duke-NUS Medical School in Singapore have developed an mRNA vaccine. One other important difference between 3-phase power vs. single phase power is the consistency of the delivery of power. Individuals. In April 2021, the European Union negotiated a deal for 1.8 billion doses, which should close up the massive shortfall they experienced early in their vaccine rollout. Vaccines that deliver one or more of the coronavirus’s own genes into our cells to provoke an immune response. The researchers hope that this combination will produce a better immune response than two doses of either vaccine. Updated Sept. 15, PHASE 1 Both kinds have been tested as vaccines over a number of years. The South Korean vaccine company SK Bioscience licensed the vaccine, called GBP510. These trials further test the vaccine’s safety. The vaccine contains small portions of viral proteins, known as peptides. The Moderna vaccine is the second one authorized by the F.D.A., coming a week after the vaccine made by Pfizer and BioNTech.Like Pfizer and BioNTech, Moderna makes its vaccine from mRNA. Because of the peaks and dips in voltage, a single-phase power supply simply does not offer the same consistency as a three-phase power supply. When the bacteria reach the intestines, the DNA slips into cells in the gut lining, which then make viral proteins. EMERGENCY USE IN U.S., ELSEWHERE On Dec. 2, Moderna registered a trial to test the vaccine on adolescents between 12 and 18 years of age. Researchers began dosing trial participants in Iran on April 26. A previous version of the tracker stated that Pfizer had reached a deal with the E.U., when in fact the deal was made by AstraZeneca. In 2019, researchers at the University of Hong Kong and Xiamen University created a nasal-spray vaccine for the flu based on a genetically weakened form of the influenza virus. The process is expected to take several months.As the trials progressed, Pfizer and BioNTech also scaled up factories to produce Comirnaty in huge amounts. Vaccines typically require years of research and testing before reaching the clinic, but in 2020, scientists embarked on a race to produce safe and effective coronavirus vaccines in record time. Some sporting events have also resumed without spectators – with snooker and racing the first to start up again, and Premier League football to follow later this month. Jay Inslee announced Thursday. The company expects a total annual manufacturing capacity of two billion doses.Yet even after millions of people began receiving the vaccine, new concerns arose. The Phase 2 trial, which is recruiting up to 1,000 volunteers, started on Jan. 5. Recommended for emergency use by the Caribbean Regulatory System. Updated May 3, PHASE 2 PHASE 3 COMBINED PHASES On Jan. 20, the company registered a Phase 1/2 trial. In recent years, the company has tested mRNA vaccines for a number of diseases, but they have yet to bring one to market. Experiments on mice showed a strong immune response. On Nov. 11, the Russian Direct Investment Fund announced the first preliminary evidence from their Phase 3 trial indicating that the vaccine is effective. Last year they constructed a vaccine for Covid-19 that presents a number of targets in the coronavirus for attack.The researchers constructed a piece of DNA that encodes the entire spike protein of the coronavirus. If the trial proved successful, the vaccine would be produced by the Iranian company CinnaGen. Updated May 7, PHASE 2 PHASE 3 COMBINED PHASES On May 5, the director of the Chumakov Center said a third dose could be necessary in some people. He also said that it’s possible that vaccinations could recur each year. Taiwan-based vaccine maker Medigen is making a vaccine made of a combination of spike proteins and an adjuvant from Dynavax. On Dec. 22, Belarus became the first country outside of Russia to register Sputnik V, and since then a number of other countries have followed suit. But the researchers have faced delays in recruiting enough participants for their Phase 1 study. Type: Muscle injection On Nov. 12, the company announced that its vaccine could be kept in a refrigerator at 41 degrees. PAUSED or ABANDONED: If investigators observe worrying symptoms in volunteers, they can pause the trial. Efficacy: 65.28% A vaccine designed by the University of Oxford and produced by the British-Swedish company AstraZeneca has emerged as a key element in the effort to meet the global demand for Covid-19 vaccines. SpyBiotech, a company spun off from the University of Oxford, announced in September that the first volunteers in an Australian Phase 1/2 trial were receiving their Covid-19 vaccine. Updated May 6, PHASE 1 In the spring, OncoSec began adapting their technology to make a vaccine for the coronavirus. Type: Nasal spray Efficacy: 72% in United States, 68% in Brazil and 64% in South Africa The company is aiming for production of a billion doses in 2021.On Nov. 16, 2020, Johnson & Johnson announced that they were also launching a second Phase 3 trial to observe the effects of two doses of their vaccine, instead of just one. In February the company registered a Phase 1 trial of an oral version of the vaccine. On March 26, they registered a small Phase 1 trial sponsored by TUBITAK, the Scientific and Technological Research Council of Turkey. beds remaining. CureVac expects the trial to show if the vaccine is safe and effective in May.In November, CureVac negotiated a deal to provide the European Union with up to 400 million doses of their vaccine. In the same month, Covax began delivering millions of doses of the vaccine to low- and middle-income countries. At the end of the two week pause, officials will evaluate the metrics and re-assess. 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